Research Interests

Ľuboš Molčan is a researcher at the Department of Animal Physiology and Ethology, Comenius University in Bratislava. His work focuses on cardiology, chronobiology, and endocrinology – especially how the cardiovascular system integrates temporal signals. He also investigates prenatal programming and the developmental origins of cardiovascular disease influenced by environmental factors.

My current research interests include:

• Circadian and ultradian rhythms in cardiovascular and behavioral functions
• Long-term telemetry in animal models (blood pressure, heart rate, EEG, activity)
• Physiological responses to environmental stress and artificial light
• Prenatal programming and developmental origins of cardiovascular disease
• Integration of chronobiology, neurophysiology, and endocrine signaling

He is also the developer of Cosinor.Online, a web-based tool for chronobiological analysis: cosinor.online.

Selected Publications

• Mauer Sutovská H, Molčan L, Štefánik P, Zeman M. Dark-phase melatonin administration does not reduce blood pressure but induces changes in cardiovascular parameters. Hypertension Research, 1–16, 2025.
• Mauer Sutovská H, Obermajer V, Zeman M, Molčan L. Artificial light at night affects the daily profile of pulse pressure and protein expression in the thoracic aorta of rats. Hypertension Research 47(7):1897–1907, 2024.
• Molčan L. Telemetric data collection should be standard in experimental cardiovascular research. Physiology & Behavior 242:113620, 2021.
• Molčan L. Time-distributed data analysis by Cosinor. Online application. bioRxiv 2019. doi:10.1101/805960
• Molčan L, Sutovská H, Okuliarová M, et al. Dim light at night attenuates circadian rhythms in the cardiovascular system and suppresses melatonin in rats. Life Sciences 231:116568, 2019.
• Molčan L, Zeman M. Shifts in the light-dark cycle increase unpredictability of the cardiovascular system. Autonomic Neuroscience 206:51–59, 2017.
• Svitok P, Molčan L, Stebelová K, et al. Prenatal hypoxia in rats increased blood pressure and sympathetic drive of the adult offspring. Hypertension Research 39(7):501–505, 2016.

Google Scholar ORCID ResearchGate Scopus

Tools and Software

I develop and maintain Cosinor.Online – a browser-based tool for analysing time-distributed data using the classic cosinor model:

Y(t) = MESOR + Amplitude × cos(2πt / Period + φ)

The tool allows users to upload time-series data, fit a cosine curve using least squares, visualise results (fit curve, polar plot, periodogram), and compare multiple groups or conditions. It is designed for chronobiological research but works with any rhythmic dataset.

Cosinor.Online

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Teaching and Supervision

Bachelor’s Level (I.)

• Bachelor Thesis in Animal Physiology and Ethology – Biology, Medical Biology
• Bachelor Seminar in Animal Physiology and Ethology (1) - (2) – Biology, Medical Biology
• Cell Biology – Biology, Systematic Biology
• Animal and Human Physiology – Biology, Systematic Biology
• Human Functional Morphology – Medical Biology

Master’s Level (II.)

• Integrative Physiology – Animal Physiology and Ethology
• Master Thesis (1)–(4) – Animal Physiology and Ethology
• Diploma Practice – Animal Physiology and Ethology
• Special Seminar (3) – Animal Physiology and Ethology
• Cardiovascular Physiology – Animal Physiology and Ethology
• Basics in Pathophysiology – Animal Physiology and Ethology
• Special Diploma Work Seminar (1) and (2) – Animal Physiology and Ethology
• Evaluation of Biological Experiments – Animal Physiology and Ethology

Doctoral Level (III.)

• Cell Signalling – Animal Physiology

More detail (AIS)

Contact

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